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Would you learn about the oral biofilm if your health depended on it? Well it just might. On the Biofilm Factor, Dr. Ryan Nolan discusses the importance of diet, biofilm management and the oral systemic link with fellow dental professionals. Join us and learn how the state of your oral cavity can impact your overall health.

For more on The Biofilm Factor, follow on Instagram @biofilmfactor and @ryannolandmd or find me on Facebook at The Biofilm Factor Podcast.

May 29, 2018


Microbial overgrowth from a poorly managed biofilm can be linked to atherosclerosis, pneumonia and other immunological conditions. Luckily, you can influence and change the types of bacteria that reside in your mouth. In this episode of The Biofilm Factor, Dr. Ryan Nolan talks with Dr. Emily Stein, co-founder of Daily Dental Care. They discuss that a diverse low sugar diet can mitigate the majority of dental risk factors. Dr. Stein also shares how to recognize good and bad bacteria living in your mouth and how to provide a hospitable oral environment for good bacteria. In addition, they discuss the inefficiencies of the one-size-fits-all mindset currently used in dentistry and the need to change to a customized approach. They conclude that being a treatment oriented society is the underlying issue behind our neglected dental health. The solution is prevention. For more on The Biofilm Factor, follow on Instagram  @biofilmfactor and @ryannolandmd or find us on Facebook at The Biofilm Factor Podcast.


Host: Dr. Ryan Nolan

Guests: Dr. Emily Stein


Bio of Dr. Emily Stein

Dr. Emily Stein is the co-founder of several biotechnology startups including Daily Dental Care, Primal Therapies and Sevident. Her work reflects her scientific background that spans from molecular biology and microbiology to cellular immunology. Her work at Daily Dental Care is focused on mitigating oral health difficulties and improving quality of life through innovative oral care products. Through her work, Dr. Stein has contributed to biofilm research and the efforts to promote prevention rather than after treatment. She can be reached on Instagram @dailydentalcare, twitter @DDCSmiles or on her website

Show Notes

  • What is Daily Dental Care and how did it get started? [1:24]
  • What makes this product unique from other products on the market? [4:56]
  • Bacteria can adapt to anything we throw at it. [6:00]
  • Dr. Stein shares what she thinks of the misuse or overuse of antibiotics. [8:18]
  • What can we do to confront biofilm? [9:50]
  • Does alcohol found in dentifrice products do anything to kill the bacteria in our mouths? [11:24]
  • Long term use of alcohol in dental products. [12:30]
  • What is the difference between prebiotics and probiotics? [13:16]
  • What are some of the unrecognized risks associated with an unmanaged biofilm and its effect on the body? [15:08]
  • Advice to dentists about the connection between the oral biofilm and health. [17:24]
  • Can this product be used prior to teeth cleaning at the dentist? [18:34]
  • Dr. Stein’s opinion on what was formerly considered the “gold standard” in dentistry. [21:02]
  • Evidence that the current options of fluoride and rinses are not sufficient. [23:14]
  • Improvements you can make to your diet to mitigate dental health risks. [25:01]
  • Who would benefit from using this product? [28:09]
  • We are changing what lives in peoples’ mouths. [29:21]
  • Even if you take out all your teeth, the biofilm does not simply go away. [31:08]
  • We are trying to change the way that bacteria behaves. [31:47]
  • What would be the difference between someone with a normal biofilm versus someone with a normal biofilm and diabetes? [32:38]
  • We can spread our oral biofilm/dental plaque to our family members by contact. [35:12]
  • There are evolutionary traits in your mouth that are different from the rest of your body. [37:05]
  • How can you avoid biofilm development in certain areas of the mouth? [39:39]
  • The controversy of the one-size-fits-all fluoride use. [41:00]
  • Personalized dentistry is the next step to addressing dental issues. [43:21]
  • Why is customized medicine a great approach for dentists? [43:40]
  • What are the immunological factors that result from a poorly managed biofilm? [45:37]
  • Is there a specific bacteria species that we should look out for? [47:57]
  • The biofilm can become smarter over time and block out helpful ions and agents. [49:18]
  • It is a problem that people are not paying attention to the influence and presence of the biofilm. [51:50]
  • Dr. Stein shares how her opinion has changed over time through research and new discovery. [53:30]
  • People are unaware of deficiencies and risk factors in their mouth. [54:33]
  • What is zero point charge? [57:13]
  • Steer your mouth towards a neutral zone and away from foods containing sugar and acid. [57:54]
  • The importance of finding an equilibrium in the mineral content of your saliva and the possible promotion of decay. [59:55]
  • We need to pay attention to the silent molecular and cellular activity for prevention. [1:02:30]
  • There is only 2.5-5% of the population that will have an ideal environment compared to the rest of the population that faces dental issues. [1:03:43]
  • What role does socioeconomics play in dental related risks? [1:05:12]
  • Biofilm damage costs the U.S. billions of dollars because we do not invest in prevention. [1:06:06]
  • Shifts in prevention methods and education that Dr. Stein is working on. [1:09:16]
  • What is the lozenge of Daily Dental Care and how does it work? [1:10:42]
  • How does Vitamin B6 work? [1:11:54]
  • Eliminating sugar fermentation and increasing protein usage in your mouth completely changes what is living in someone’s biofilm. [1:13:10]
  • Dr. Stein shares how the Daily Dental Care helped her grandmother. [1:15:10]
  • You can recreate someone’s biofilm to repair his or her oral health. [1:16:14]
  • Where can you buy the Dental Diet Care products? [1:16:55]
  • Closing information about Dr. Emily Stein and her team. [1:17:20]